Progress and challenge of neoadjuvant therapy for breast cancer
10.3969/j.issn.1005-6483.2018.01.024
- VernacularTitle:乳腺癌新辅助治疗的进展
- Author:
Wenjing LIU
1
;
Yan MAO
;
Haibo WANG
Author Information
1. 青岛大学附属医院
- Keywords:
breast cancer;
neoadjuvant therapy;
progress
- From:
Journal of Clinical Surgery
2018;26(1):73-76
- CountryChina
- Language:Chinese
-
Abstract:
With the development of medical technology,the treatment of breast cancer has en-tered into a comprehensive treatment age which combines chemotherapy,radiotherapy,endocrine therapy and molecular targeting therapy from the time of local treatment. Neoadjuvant therapy has been widely ap-plied in clinic due to many advantages,such as lowering the primary breast tumor and axillary lymph node,improving breast conserving rate and predicting drug sensitivity. With the emergence of molecular typing of breast cancer,neoadjuvant therapy has changed from primary neoadjuvant chemotherapy to the comprehensive treatment with neoadjuvant chemotherapy,neoadjuvant endocrine therapy and neoadjuvant targeted therapy. Here is a review of the progress of neoadjuvant therapy,evaluation of curative effect,se-lection of operation mode and challenges of neoadjuvant therapy from different molecular typing of breast cancer.
