Association of Th17 cells, regulatory T cells, and their imbalance with nonalcoholic fatty liver disease
10.3969/j.issn.1001-5256.2018.06.046
- VernacularTitle:辅助性T淋巴细胞17和调节性T淋巴细胞及其平衡改变与非酒精性脂肪性肝病的关系
- Author:
Weihua GAO
1
;
Kuanxue GE
;
Xiaoxing XIANG
Author Information
1. 扬州大学医学院
- Keywords:
nonalcoholic fatty liver disease;
T -lymphocytes;
helper -inducer;
T -lymphocytes;
regulatory;
review
- From:
Journal of Clinical Hepatology
2018;34(6):1347-1350
- CountryChina
- Language:Chinese
-
Abstract:
Nonalcoholic fatty liver disease (NAFLD) is closely associated with insulin resistance and genetic susceptibility and is one of the chronic liver diseases that threaten human health .Under certain conditions, Th17 cells and regulatory T (Treg) cells can be transformed to each other to maintain immune homeostasis.In recent years, more and more studies have been performed on the involvement of Th 17 and Treg cells in the development and progression of liver diseases .Th17 cells, Treg cells, and their balance may become the new targets for the treatment of NAFLD.This article reviews the latest research advances in the association of Th 17 and Treg cells with NAFLD and the role of Th17/Treg balance in the development and progression of NAFLD .
