Role of extracellular vesicles in the development and progression of liver diseases
10.3969/j.issn.1001-5256.2018.03.048
- VernacularTitle:细胞外囊泡与肝脏疾病发生发展的关系
- Author:
Jiangyu WANG
1
;
Zhixin WANG
;
Haining FAN
Author Information
1. 青海大学
- Keywords:
extracellular vesicles;
hepatitis,viral;
human;
liver cirrhosis;
liver cancers;
liver neoplasms;
review
- From:
Journal of Clinical Hepatology
2018;34(3):653-657
- CountryChina
- Language:Chinese
-
Abstract:
Extracellular vesicles(EVs)are membrane-bound vesicles released by cells into the extracellular environment and can selec-tively enrich specific proteins and RNA and mediate intercellular communication. Therefore,EVs have the potential of a biomarker for disea-ses,a therapeutic target,and a delivery vector. This article reviews the research advances in the role of EVs in viral hepatitis,liver fibrosis, and liver cancer and emphasizes the prospects of EVs in liver diseases.