Features and management of patients with hepatitis C virus/hepatitis B virus dual infection associated with the application of direct-acting antiviral agents

VernacularTitle:与直接抗病毒药物应用相关的HCV/HBV双重感染的特点及其诊治管理
Author: Yuecheng YU ¹ ; Ye FAN ; Ping LI
Author Information

1. 南京中医药大学附属八一医院全军肝病中心
Keywords: hepacivirus; hepatitis B virus; superinfection; diagnosis; therapy
From: Journal of Clinical Hepatology 2018;34(2):238-241
CountryChina
Language:Chinese
Abstract: Dual infection with hepatitis C virus (HCV) and hepatitis B virus (HBV) has significantly different clinical,immunological,and virological features from single infection with HCV or HBV,which brings various challenges to clinical diagnosis/treatment and management.Direct-acting antiviral agents used for effective control of HCV infection may cause HBV activation,onset of hepatitis B,and even liver failure.Therefore,during the antiviral treatment of HCV infection,it is of great importance to select appropriate anti-HBV therapy and follow-up management strategies based on the status of HCV/HBV dual infection.