The role of physical examination, pulse oximetry screening, and perfusion index in screening of neonatal congenital heart disease
10.3969/j.issn.1000-3606.2018.03.002
- VernacularTitle:体格检查、脉搏血氧饱和度筛查和灌注指数在新生儿先天性心脏病筛查中的作用
- Author:
Cheng PAN
1
;
Xiaoming ZOU
;
Gang CHEN
;
Tao WANG
;
Xianyu JIANG
;
Jianyong CHEN
Author Information
1. 南方医科大学南方医院
- Keywords:
physical examination;
pulse oximetry screening;
perfusion index;
congenital heart disease;
screening
- From:
Journal of Clinical Pediatrics
2018;36(3):166-169
- CountryChina
- Language:Chinese
-
Abstract:
Objective To find a reliable, simple, and easily-operated method for the screening of neonatal congenital heart disease (CHD). Methods A total of 7 105 neonates born from January 2017 to July 2017 were selected. The validity and reliability of physical examination, pulse oximetry screening (POS), and perfusion index (PI) in the screening of neonatal CHD were evaluated according to the diagnosis made by color Doppler echocardiography. Results When physical examination, POS or PI was used separately in screening for CHD, the sensitivities were in the range of 13.11%~73.77%, specificities 50.20%~99.34%, Youden indexes 0.12~0.70, the total coincidence rates 50.40%~98.86%, positive predictive values 1.27%~40.70%, and negative predictive values 99.29%~99.70%. When physical examination, POS and PI were combined (two or three indexes were positive) for screening, the sensitivities and Youden indexes were 85.25% and 0.82 respectively, which were higher than those of single indicators and suggested that the combination had higher authenticities. The total coincidence rate of the combination was 97.07%, and, although it was lower than POS group (98.86%) and PI screening group (98.58%), it still had a good reliability. Conclusions The combination of physical examination, POS and PI has a certain clinical value in neonatal CHD screening.
