Clinical analysis of 8 cases of neonatal hand-foot-mouth disease

VernacularTitle:新生儿手足口病8例临床分析
Author: Gaofeng ZHOU ¹ ; Hongmei WANG ; Shufeng TIAN ; Jikui DENG
Author Information

1. 深圳市儿童医院感染科广东深圳 518038
Keywords: hand-foot-mouth diseases; enterovirus; neonatal
From: Journal of Clinical Pediatrics 2017;35(11):857-859
CountryChina
Language:Chinese
Abstract: Objective To study the clinical features,treatment and prognosis of neonatal hand-foot-mouth disease.Methods Neonatal hand-foot-mouth disease patients admitted from July 2014 to May 2016 were retrospectively studied.EV71,CA16 and universal enterovirus were detected from newborn swabs by RT-PCR.Results A total of 8 neonatal patients with hand-foot-mouth diseases,6 boys and 2 girls were diagnosed at an age ranged from 7-26 days.Of them,7 patients had exposure history.Clinical manifestations including rash (8 cases),fever (6 cases),irritability (4 cases) and vomiting (1 case),nobody suffered convulsions.The results of RT-PCR showed pathogen enterovirus not-EV71 and not-CA16.There were 5 cases of pulmonary infection treated with antibiotic therapy.All of the 8 cases had a good prognosis.Conclusions Most of the handfoot-mouth diseases had exposure history without specific clinical manifestations.They had not-EV71 and not-CA16 intestinal virus infection,some patients had pulmonary infection.Therefore,neonatal hand-foot-mouth diseases need more clinical attention.