Chemerin in Obstructive Sleep Apnea-hypopnea Patients' Pharyngeal Fat Deposition
10.3969/j.issn.1003-4706.2018.01.018
- VernacularTitle:趋化素与阻塞性睡眠呼吸暂停低通气综合征患者咽部脂肪沉积的相关性
- Author:
Hai-Ying WU
1
;
Shou-Ming CAO
;
Bin SHI
;
Zhong BAI
;
Yong-Xia LI
Author Information
1. 昆明医科大学第二附属医院耳鼻咽喉科
- Keywords:
Obstructive sleep apnea-hypopnea syndrome;
Chemerin;
Metabolic Syndrome
- From:
Journal of Kunming Medical University
2018;39(1):77-80
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the effect of chemerin on the pharyngeal fat deposition by comparing the level of chemerin of fat tissue in pharynx between the patients with OSAHS and non-snorer. Methods OSAHS patients finished PSG and non-snoring patients with tonsillitis as controlled group were examined to observe their chemerin level of space veli palatine. Comparisons of the chemerin level and the indexes of MS were made to analyze the relationship between chemerin and MS. Results The level of chemerin of space veli palatine in OSAHS patients was higher than that of the control groups. And the level of chemerin within the OSAHS patients also had positive correlation with TG、HOMA-IR and uric acid. We also found that the TG, HDL-C, FINS, HOMA-IR and the uric acid had statistical differences ( <0.05) between the two groups. Conclusion The level of chemerin of OSAHS group is exceed the control group and positively related with indexes of MS. Chemerin may take part in the development of fat deposition in pharynx of OSAHS patients , which may be through MS pathway.
