The Establishment of Porcine Scoliosis Model by the Adjustable Brace Asymmetric Tethering

VernacularTitle:可调节支具不对称固定建立幼猪无创脊柱侧凸模型
Author: Wei-Yun KONG ¹ ; Chong-Wen MAO ; Jun-Wei SHAO ; Xue-Fang TANG ; Fei WANG ; Wei XU ; Kai-Yu HOU ; Quan ZHOU
Author Information

1. 昆明医科大学第四附属医院骨科
Keywords: Scoliosis; Porcine; Animal model
From: Journal of Kunming Medical University 2018;39(1):26-29
CountryChina
Language:Chinese
Abstract: Objective To explore the feasibility of the adjustable brace asymmetric tethering in concave side for establishing a porcine scoliosis model.Methods Six minority piglets (aged 8-10-week-old, weight 8-10 kg) were selected and the adjustable brace asymmetric tethering in concave side were applied during the procedure.Roentgenography was performed before and immediately after the operation, and 1, 2 and 3 months after the procedure.Cobb angles were measured based in the plain radiograph.Results A piglet died for narcotic drug overdose and the other 5 pigs succeeded in modeling.The cobb angles were (9.0 ±1.6) ° in one month, (11.8 ±1.3) ° in two months and (21.6 ±2.4) ° in three months after the operation . Conclusion It's is an effective way to establish the porcine model of rapidly progressive structural scoliosis by the adjustable brace asymmetric tethering in concave side.It avoids the damage to the spinal elements and could be an ideal model for further study on corrective techniques.