The clinical observation of the platelet parameters in patients with acute myocardial infarction in plateau
10.3760/cma.j.issn.1671-0282.2018.07.006
- VernacularTitle:高原地区急性心肌梗死患者血小板参数的临床观察
- Author:
Ling LIN
1
;
Wei ZHANG
;
Lichao FANG
;
Wujian HE
;
Shigang QIAO
;
Fuqi XU
Author Information
1. 青海省人民医院急诊科
- Keywords:
Plateau;
Acute myocardial infarction;
Platelet distribution width;
Mean platelet volume;
Prognosis
- From:
Chinese Journal of Emergency Medicine
2018;27(7):735-739
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical value of platelet parameters in patients with acute myocardial infarction(AMI) in plateau.Methods A total of 72 patients diagnosed as acute myocardial infarction in our department from January 2016 to June 2017 were enrolled into this study.Clinical data and outcomes were analyzed.Platelet parameters were measured within 24 h after AMI occurrence.The relationship between platelet distribution width (PDW),mean platelet volume (MPV),and the severity of disease,infarct size as well as short-term prognosis were further investigated.Results Compared with control group,PDW and MPV were positively correlated with the severity of disease (PPDW=0.039,PMPV=0.038) and infarct size (rPDW=0.305,P=0.009;rMPV=0.263,P=0.025).The AUC of PDW was 0.827,optimal operating point (OOP) was 16.3％,the AUC of MPV was 0.813,OOP was 13.1 fl,the AUC of GRACE was 0.865,OOP was 145.Conclusions PDW and MPV could be regarded as laboratory index to evaluate the severity of disease,infarct size,pathological changes of coronary artery and short-term prognosis of acute myocardial infarction in plateau.
