Current development of fluorescent probes for cellular reactive oxygen species
10.7644/j.issn.1674-9960.2018.01.018
- VernacularTitle:细胞活性氧荧光探针研究现状
- Author:
Quan ZHOU
1
;
Guo-Yang HUANG
;
Wei-Gang XU
Author Information
1. 海军军医大学海军医学系潜水医学教研室
- Keywords:
fluorescent probes;
reactive oxygen species;
mitochondria
- From:
Military Medical Sciences
2018;42(1):72-76
- CountryChina
- Language:Chinese
-
Abstract:
Reactive oxygen species(ROS)plays an important role in physiological and pathological processes in cells. Different effects can be produced depending on the type and subcellular localization of ROS.Therefore,various fluorescent probes have been developed to quantify and localize ROS specifically.However,due to technical limitations,these probes have defects in specificity and stability.In this paper, we review existing cellular and mitochondrial ROS probes, and summarize their characteristics.