CT-guided percutaneous transthoracic needle biopsy for the diagnosis of non-small cell lung cancer: a retrospective analysis of its diagnostic accuracy
10.3969/j.issn.1008-794X.2018.03.019
- VernacularTitle:CT引导下经皮肺穿刺活检术诊断肺癌准确性的回顾性分析
- Author:
Lan HU
1
;
Qing GUO
;
Dan WEN
;
Jing YAN
;
Yong DU
Author Information
1. 637000,四川南充川北医学院附属医院放射科
- Keywords:
lung;
puncture biopsy;
pathological classification;
diagnostic accuracy
- From:
Journal of Interventional Radiology
2018;27(3):274-277
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic accuracy of CT-guided percutaneous transthoracic needle biopsy (PTNB) for non - small cell lung cancer (NSCLC), and to discuss the factors affecting the diagnostic accuracy of puncture biopsy. Methods The clinical data of a total of 203 patients with pathologically-proved NSCLC, who received CT-guided PTNB during the period from January 1, 2010 to November 1, 2016, were retrospectively analyzed. CT - guided PTNB was performed in all patients before surgery, and tissue specimens were collected for pathological study. The diagnostic accuracy of needle biopsy was calculated, and the factors that might affect the diagnostic accuracy of needle biopsy were analyzed. Results (l)The coincidence rate of pathological results of CT-guided PTNB (small specimens) with surgical specimens (large specimens) was 92. 6％ (188/203). The squamous cell carcinoma and adenocarcinoma had the highest coincidence rates, which were 100％ and 97. 5％ respectively. The coincidence rate of large cell carcinoma type was 20％. No statistically significant differences in the coincidence rate of adenocarcinoma and squamous cell carcinoma existed between small specimens and large specimens (κ=0. 872, P=0. 250). (2)Chi square test showed that only the lesion size was an important factor that affected the diagnostic accuracy of needle biopsy (P=0. 008). Conclusion In diagnosing commonly seen NSCLC, CT - guided PTNB has high coincidence rate with surgical specimens, therefore, CT-guided PTNB is worth popularizing widely in clinical practice. The lesion size is an important factor that affected the diagnostic accuracy of needle biopsy. (J Intervent Radiol, 2018, 27:274-277)
