Irreversible electroporation ablation of tumor: an analysis of perioperative complications
10.3969/j.issn.1008-794X.2018.03.007
- VernacularTitle:不可逆电穿孔消融肿瘤围手术期并发症分析
- Author:
Zilin QIN
1
;
Lizhi NIU
;
Bing LIANG
;
Liang ZHOU
;
Gang FANG
;
Wei QIAN
;
Weibing ZHU
;
Jiongyuan XU
;
Yong HU
;
Jianying ZENG
;
Jibing CHEN
;
Kecheng XU
Author Information
1. 510632,广州 暨南大学医学院
- Keywords:
irreversible electroporation ablation;
tumor;
perioperative period;
adverse effect
- From:
Journal of Interventional Radiology
2018;27(3):223-227
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize and analyze the perioperative complications of irreversible electroporation (IRE) ablation in treating tumors at different locations and to discuss their managements. Methods A total of 200 patients with tumors, including pancreatic tumor (n=71), liver tumor (n=64) and other tumors (n =65), were enrolled in this study. All patients received IRE ablation treatment. The perioperative complications were recorded and the data were statistically analyzed. The causes of severe complications and the treatment of complications were discussed. Results None of the patients died during the course of IRE ablation procedure. Severe postoperative complications occurred in the patients with pancreatic tumor or liver tumor, including duodenal artery bleeding in 3 patients with pancreatic tumor, which occurred at 10 days, 11 days and 15 days after IRE ablation respectively, and gastrointestinal bleeding (n =1) and biliary septic shock (n=1) in 2 patients with liver tumor, which occurred at 9 days after IRE ablation, the clinical symptoms were controlled after interventional embolization and/or vascular ligation together with anti-infective therapy. All minor complications were relieved after symptomatic treatment within 14 days. Conclusion IRE ablation has less systemic inflammatory response, and both the intraoperative and postoperative adverse reactions can be easily controlled, besides, IRE ablation has higher clinical safety. Although IRE ablation procedure may damage the internal or peripheral vessels of the pancreatic tumor, this severe complications can be effectively avoided if proper measures are adopted based on the causes of complications. (J Intervent Radiol, 2018, 27: 223-227)
