Side effects and complications of yttrium-90 radioembolization therapy for hepatic malignancies. A series review of radioembolizat(i)on with 90Y microspheres(part V)
10.3969/j.issn.1008-794X.2018.02.022
- VernacularTitle:钇-90微球放射栓塞治疗肝脏恶性肿瘤的不良反应和并发症——钇-90微球放射栓塞系列回顾(五)
- Author:
Lili ZHENG
1
;
Zhongzhi JIA
;
Sini WANG
;
Weiping WANG
Author Information
1. 325000,浙江 温州医科大学附属第一医院放射科
- Keywords:
yttrium-90;
radioembolization;
side effects;
complications
- From:
Journal of Interventional Radiology
2018;27(2):190-196
- CountryChina
- Language:Chinese
-
Abstract:
Radioembolization with yttrium-90(90Y) microspheres is an alternative treatment choice for hepatic malignancies and has become incorporated into guidelines by many international oncology and other professional organizations. The tumoricidal effects of radioembolization are predominantly derived from its radioactivity rather than ischemia. Therefore, the overall side effects that have been associated with this therapy, such as fatigue, nausea and vomiting, which are mild but common. Occasionally, severe complications may occur due to incidental embolization of non-target tissue by the microspheres. This review describes in detail the manifestation of side effects and various complications that may be associated with radioembolization using 90Y microspheres. Management and treatment options of these potential adverse events will also be discussed briefly.
