Argon-helium knife cryoablation for the treatment of liver metastases from gastric cancer
10.3969/j.issn.1008-794X.2018.01.010
- VernacularTitle:氩氦刀冷冻消融挽救治疗胃癌肝转移患者
- Author:
Xu CHANG
1
;
Zhi GUO
;
Haipeng YU
;
Tongguo SHI
;
Weihao ZHANG
;
Xueling YANG
Author Information
1. 300060,天津医科大学肿瘤医院介入科、国家肿瘤临床医学研究中心、天津市肿瘤防治重点实验室、天津市恶性肿瘤临床医学研究中心
- Keywords:
liver metastasis;
cryoablation;
percutaneous puncture ablation;
safety
- From:
Journal of Interventional Radiology
2018;27(1):40-44
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the curative effect and safety of percutaneous argon-helium knife cryoablation in treating patients with liver metastases from gastric cancer.Methods The clinical data of 24 patients with liver metastases from gastric cancer,who had received percutaneous argon-helium knife cryoablation therapy,were retrospectively analyzed.A total of 33 metastatic lesions could be used for evaluation.CT-guided percutaneous argon-helium knife cryoablation of liver metastases was carried out in all patients.The 3-month,6-month and 12-month local control rate,overall survival (OS) rate,progression -free survival (PFS),incidence of recurrence,preoperative and postoperative quality of life,and complications were documented.Results The median follow-up time was 14 months (6-48 months).After cryoablation therapy,the quality of life was improved significantly.The 3-month,6-month and 12-mouth local control rates were 91.7％,73.9％ and 52.6％ respectively.Mter cryoablation therapy,the median PFS was 8 months (1-16 months),the median survival time was 16 months,and the one-year and 2-year survival rates were 75.0％ and 37.5％ respectively.No severe complications occurred.Conclusion For the treatment of liver metastases from gastric cancer,percutaneous argon-helium knife cuoablation is safe and effective with reliable short-term curative effect,the patient's quality of life can be well improved.
