Selective arterial embolization for the treatment of spontaneous rupture with bleeding of hepatocellular carcinoma: analysis of curative effect and prognosis
10.3969/j.issn.1008-794X.2017.12.007
- VernacularTitle:选择性动脉栓塞治疗原发性肝癌自发破裂出血的疗效及预后分析
- Author:
Chun ZHOU
1
;
Sheng LIU
;
Qingquan ZU
;
Bin WANG
;
Shaoxian WANG
;
Haibin SHI
Author Information
1. 210029,南京医科大学第一附属医院介入放射科
- Keywords:
hepatocellular carcinoma;
spontaneous rupture;
transarterial embolization;
efficacy;
prognostic factor
- From:Journal of Interventional Radiology
2017;26(12):1093-1097
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the curative effect of transarterial embolization (TAE) for the treatment of spontaneous rupture with bleeding of hepatocellular carcinoma (HCC),and to discuss the factors influencing prognosis.Methods A total of 57 patients with HCC complicated by spontaneous rupture and bleeding,who received initial TAE during the period from June 2012 and June 2016,were enrolled in this study.The last follow-up visit was in October 2016.Kaplan-Meier method was used to calculate the cumulative survival rate,and Cox regression model was adopted to analyze prognostic factors.Results In this series of 57 patients,the median survival time was 208 days.The 6-month,1-year and 2-year cumulative survival rates were 50.3％,35.9％ and 14.7％,respectively.Multivariate Cox regression analysis indicated that tumor size,Child-Pugh classification,history of shock,and the used embolization materials were the independent prognostic factors.Conclusion The use of selective TAE,as an initial therapy,for HCC complicated by spontaneous rupture and bleeding is safe and effective.This study reveals that larger diameter of the tumor,poor Child-Pugh classification,the presence of shock history indicate a poor prognosis.TACE using lipiodol combined with gelatin sponge particles can expect a better prognosis than TACE using PVA particles alone.
