Research progress in treatment of cryptogenic stroke associated with patent foramen ovale
10.11855/j.issn.0577-7402.2018.04.17
- VernacularTitle:卵圆孔未闭相关隐源性卒中的治疗研究进展
- Author:
Li-Hua MA
1
;
Xiu-Li LI
;
Hao HU
;
Man-Xia WANG
Author Information
1. 730000兰州,兰州大学第二医院神经内二科
- Keywords:
patent foramen ovale;
cryptogenic stroke;
anticoagulant;
antiplatelet;
PFO closure
- From:
Medical Journal of Chinese People's Liberation Army
2018;43(4):356-360
- CountryChina
- Language:Chinese
-
Abstract:
Patent foramen ovale (PFO) is a common congenital heart disease that can cause cryptogenic stroke through paradoxical embolization.For patients with PFO combined with cryptogenic stroke,whether anticoagulant therapy is superior to antiplatelet therapy in the prevention of recurrent stroke? And whether PFO closure can significantly reduce the risk of stroke recurrence compared with medical therapy alone? All those raised the clinical problems to be solved urgently.The advances in treatment of cryptogenic stroke associated with PFO are herewith summarized in present paper by reviewing randomized trials,meta-analyses and the guidelines or expert consensus about PFO and cryptogenic stroke.