Research progress of exosomes in treating spinal cord injury
- VernacularTitle:外泌体治疗脊髓损伤的研究进展
- Author:
Dong-Ling SHI
1
;
Bing-Qian HE
;
Ling-Hao DAI
Author Information
1. 浙江中医药大学 中医药科学院
- Keywords:
spinal cord injury;
exosomes;
mesenchymal stem cells
- From:
Basic & Clinical Medicine
2018;38(6):849-852
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are membrane vesicles secreted by cells into the extracellular environment. Exosomes are a new cell component in the treatment of spinal cord injury. Exosomes are secreted by mesenchymal stem cells have anti-apoptotic, anti-inflammatory and pro-angiogenic effects in the treatment of spinal cord injury, which play a key role in nerve cell-cell communication and can delivery exogenous genetic material. Exosomes can penetrate blood-brain barrier and are more stable than their parent cells, reducing the safety risks in the administration of viable cells.
