Advances in research on tumor targeted therapy of trastuzumab
- VernacularTitle:曲妥珠单抗对肿瘤靶向治疗的研究进展
- Author:
Sheng-Long GU
1
;
Rui ZHAO
;
Miao-Fa YING
;
Ming-Xing LI
Author Information
1. 浙江大学医学院附属邵逸夫医院药剂科
- Keywords:
Her2;
trastuzumab;
tumor targeted therapy;
mechanisms;
research advances
- From:
Basic & Clinical Medicine
2018;38(5):722-726
- CountryChina
- Language:Chinese
-
Abstract:
Trastuzumab is a humanized monoclonal antibody that targets at human epidermal growth factor receptor 2(Her2)proto-oncogenes,which can act on Her2 over-expression of tumor cells,inhibits tumor cells proliferation, differentiation,migration and other physiological activities,reduces the risk of tumor metastasis and extend the sur-vival time of patients.
