Research advances on the role of extracellular matrix in pulmonary fibrosis
- VernacularTitle:细胞外基质在肺纤维化中作用的研究进展
- Author:
Cheng-Cheng LIU
1
;
Lin-Xiang ZENG
Author Information
1. 南昌大学第二附属医院呼吸内科,江西南昌330006
- Keywords:
extracellular matrix;
pulmonary fibrosis;
biomechanical property
- From:
Basic & Clinical Medicine
2018;38(5):698-702
- CountryChina
- Language:Chinese
-
Abstract:
Pulmonary fibrosis(PF)is characterized by extensive deposition of extracellular matrix(ECM),changes in biomechanical properties of ECM result from the process of PF actively drive disease progression.Several matrix protein candidates correlate with fibrotic pathologies,ECM may offer many novel therapeutic targets.