Research progress in long non-coding RNAs involved in invasion and metastasis of breast cancer
10.3969/j.issn.1001-6325.2018.04.031
- VernacularTitle:长链非编码RNA调控乳腺癌侵袭与转移的研究进展
- Author:
Zi-Gui ZOU
1
;
Jin-Xing ZHOU
;
Tian-Shi MA
;
Zhi-Hong ZHANG
Author Information
1. 南京医科大学第一附属医院 病理科
- Keywords:
long non-coding RNA;
breast cancer;
invasion and metastasis
- From:
Basic & Clinical Medicine
2018;38(4):573-577
- CountryChina
- Language:Chinese
-
Abstract:
Long non-coding RNAs(lncRNAs) defined as RNAs of more than 200 nucleotides in length don't en-code protein but are closely related to the development of breast cancer.Plenty of lncRNAs are dysregulated in breast cancer,and they can regulate the invasion and metastasis of breast cancer through various mechanisms such as transcription and post-transcriptional regulation which is greatly important to guide the treatment and prognosis of breast cancer.
