Progress in the mechanism study on colitis associated cancer
10.3969/j.issn.1001-6325.2018.04.030
- VernacularTitle:结肠炎相关结肠癌机制研究进展
- Author:
Hua-Chen SONG
1
;
Xiao-Nan TANG
;
Hai-Jing ZHANG
;
Wen-Jie WANG
;
Lian-Qiu WU
Author Information
1. 中国医学科学院 北京协和医学院 药物研究所 天然药物活性物质与功能国家重点实验室
- Keywords:
ulcerative colitis;
colitis-associated colon cancer;
pathogenesis mechanism
- From:
Basic & Clinical Medicine
2018;38(4):568-572
- CountryChina
- Language:Chinese
-
Abstract:
The ulcerative colitis is closely related to colitis associated cancer.The main mechanisms related to the occurrence,development and malignant transformation of CAC includes NF-κB pathway,signal transducers and ac-tivator of transcription(STAT) and related protein pathways,intestinal microflora imbalance,the immune microen-vironment,Toll-like receptor (TLR)-related pathway and so on.
