ESE-3 transcription factor and tumorigenesis
- VernacularTitle:ESE-3转录因子与肿瘤发生
- Author:
Jia-Yan WU
1
;
Yong-Qing TAO
;
Zhi-Bo HAN
Author Information
1. 天津商业大学 生物技术与食品科学学院 天津市食品生物技术重点实验室
- Keywords:
ESE-3 factors;
cancer
- From:
Basic & Clinical Medicine
2018;38(3):400-404
- CountryChina
- Language:Chinese
-
Abstract:
ESE-3 belongs to the epithelium-specific ETS transcription factor subfamily of ETS (E26) located in chromosome 11p12. It belongs to the transcriptional regulation factor which forms transcription complexes with its effector molecules, enhancing or inhibiting transcription of different downstream target genes. The expression of ESE-3 is abnormal in many kinds of tumors, such as colon cancer, pancreatic cancer, prostate cancer, breast cancer and so on. It suggests that ESE-3 plays an important role on the pathogenesis of various tumors.
