Progress on the relationship between lncRNA-CCATl and gastrointestinal cancer
- VernacularTitle:IncRNA-CCATl与消化道肿瘤关系的研究进展
- Author:
Jing-Lin LI
1
;
Wang-Yang ZHENG
;
Xin-Heng LI
;
Zheng-Long LI
;
Zhi-Dong WANG
;
Yun-Fu CUI
;
Xing-Ming JIANG
Author Information
1. 哈尔滨医科大学附属第二医院 胆胰外科
- Keywords:
IncRNA;
CCAT1;
gastrointestinal cancer
- From:
Basic & Clinical Medicine
2018;38(2):237-240
- CountryChina
- Language:Chinese
-
Abstract:
Colon cancer associated transcript 1 (CCAT1) is a kind of long non-coding RNA (IncRNA) found re-cently, which is aberrant overexpression in colorectal cancer, and it can promote cancer cell proliferation, invasion and metastasis. CCAT1 involves in the regulation of multiple pathophysiological processes, especially the formation and progression of gastrointestinal cancer, through the interaction with microRNA (miRNA) or protein by regulation mechanism like endogenous competition, and it is expected to serve as a valuable biomarker and therapeutic target.