Research progress in renal injury relevant to primary Sj(o)gren's syndrome
10.11817/j.issn.1672-7347.2018.03.014
- VernacularTitle:原发性干燥综合征肾损害研究进展
- Author:
Yao ZOU
1
;
Guanghui LING
;
Jing TIAN
;
Jinwei CHEN
;
Yan GE
Author Information
1. 中南大学湘雅二医院风湿免疫科
- Keywords:
primary Sj(o)gren's syndrome;
kidney damage;
clinical manifestation;
pathology;
treatment
- From:
Journal of Central South University(Medical Sciences)
2018;43(3):320-326
- CountryChina
- Language:Chinese
-
Abstract:
Primary Sj(o)gren's syndrome (pSS) is a chronic autoimmune disease characterized by lymphoplasmacytic infiltration of the exocrine glands that results in multiple organs and systems damage.Renal injury affects 0.3％-27.0％ patients,The most frequent form of nephropathy in pSS is tubulointerstitial nephritis.The main clinical manifestation is renal tubular acidosis.The renal prognosis in patients with pSS is usually favorable,but renal failure may occur.At present,it still lacks of strict consensus or guideline for the treatment.
