Correlation between cerebrovascular hemodynamic index accumulative score and subclinical arteriosclerosis indicators
10.11817/j.issn.1672-7347.2018.02.016
- VernacularTitle:脑血管血流动力学积分值与亚临床动脉硬化指标的相关性
- Author:
Lei LIU
1
;
Yaqin WANG
;
Zhongyang HU
;
Pinting YANG
;
Xia CAO
;
Ting YUAN
;
Guilian WANG
;
Zhiheng CHEN
Author Information
1. 中南大学湘雅三医院健康管理中心
- Keywords:
cerebrovascular hemodynamic index;
subclinical arteriosclerosis;
serum cystain C;
microalbuminuria
- From:
Journal of Central South University(Medical Sciences)
2018;43(2):198-203
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the correlation between cerebrovascular hemodynamic index (CVHI) accumulative score and subclinical arteriosclerosis indicators.Methods:A total of 27 184 cases were collected from the Health Management Center,the Third Xiangya Hospital,Central South University.Linear regression analysis was carried out to confirm the correlations between CVHI accumulative score and the modified Framingham stroke profile (FSP),as well as between CVHI accumulative score and cerebrovascular diseases (ICVD) scale.The correlation between CVHI accumulative score and brachial-ankle pulse wave velocity (baPWV),carotid plaque orcarotid intima-media thickness (CIMT) was analyzed by multifactor logistic regression model in 11 580 cases.Moreover,the correlation between CVHI accumulative score and microalbuminuria or serum cystatin C was performed by multifactor logistic regression model in 9 860 cases.Results:In this study,the people whose CVHI accumulative score was less than 75 accounted for 12.98％.The CVHI accumulative score was negatively related with the modified FSP score (r=-0.484,P＜0.01) or ICVD score (r=-0.455,P＜0.01).The multifactor logistic regression model found that the baPWV,carotid plaque,microalbuminuria and serum cystatin C were independent predictors for CVHI accumulative score.Conclusion:The CVHI accumulative score is correlated with the modified FSP score,ICVD score and indexes of subclinical arteriosclerosis (baPWV,carotid plaque,microalbuminuria and serum cystatin C).The CVHI accumulative score could be used as a tool for zero-level and primary prevention of cerebral stroke.
