Efficacy of combination of ozonated water with oil for treatment of tinea pedis
10.11817/j.issn.1672-7347.2018.02.007
- VernacularTitle:臭氧水联合臭氧油治疗足癣的疗效
- Author:
Jianyun LU
1
;
Min GUO
;
Hongfa LIGUI
;
Kathy WU
;
Yaping XIANG
;
Jinhua HUANG
;
Lihua GAO
Author Information
1. 中南大学湘雅三医院皮肤科
- Keywords:
tinea pedis;
ozonated water;
ozonated oil;
naftinfine hydrochloride and ketoconazole cream
- From:
Journal of Central South University(Medical Sciences)
2018;43(2):147-151
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate efficacy of combined therapy with ozonated water and oil on patients with tinea pedis.Methods:A total of 60 patients with tinea pedis were divided into 2 groups in a randomized and blinded test.Patients in a control group were treated with naftinfine hydrochloride and ketoconazole cream once a day.Patients in an ozone group were treated with ozonated water bath and then ozonated oil topical application once a day.Patients in the 2 groups were treated for 4 weeks.Clinical and laboratory data were collected for both groups at the end of the 1st week,the 2nd week,and the 4th week.The Pearson chi-square was performed to compare scores of the clinical signs and symptoms (CSS) and the mycological result between the 2 groups.Independent samples T-test was performed to compare the curative effect between the 2 groups.Results:After 4 weeks' treatment,6 patients were positive in the control group determined by mycological examination while 1 patient was positive in the ozone group,with no significant difference between the 2 groups (P＞0.05).Changes in CSS at the end of the 1st week,2nd week,and 4th week were obtained and showed no significant difference between the 2 groups at the 3 different time points (P＞0.05).No side effects were observed.Conclusion:Combination of ozonated water with oil is effective on treatment oftinea pedis and it shows no side effects.
