NMDA receptor and its role in cardiovascular diseases
10.11817/j.issn.1672-7347.2017.11.012
- VernacularTitle:NMDA受体及其与心血管疾病关系的研究进展
- Author:
Jinyan XIE
1
;
Kui HONG
Author Information
1. 南昌大学第二附属医院分子医学重点实验室
- Keywords:
glutamic acid receptor;
NMDAR;
disease of cardiovascular system
- From:
Journal of Central South University(Medical Sciences)
2017;42(11):1316-1320
- CountryChina
- Language:Chinese
-
Abstract:
Cardiovascular disease is the main threat to human health,which is one of the important causes of death in worldwide.N-methyl-D-aspartate receptor (NMDAR) is one of crucial ionic glutamate receptors.The physiology and pharmacology function of the composition of NMDAR are very complicated.Researches have shown that NMDAR with a high permeability to calcium and a unique feature of controlling numerous calcium-dependent processes.NMDAR affects the occurrence and development of cardiovascular disease such as hypertension,arrhythmia,myocardial infarction.
