Research progress in DEAD-box family protein in cancer
10.11817/j.issn.1672-7347.2017.11.011
- VernacularTitle:DEAD-box家族蛋白在癌症中的研究进展
- Author:
Xiaohong WEN
1
;
Shufang ZHANG
;
Ying'ai ZHANG
Author Information
1. 中南大学湘雅医学院附属海口医院中心实验室
- Keywords:
DEAD-box family proteins;
RNA helicase;
cancer;
targeted therapy
- From:
Journal of Central South University(Medical Sciences)
2017;42(11):1311-1315
- CountryChina
- Language:Chinese
-
Abstract:
DEAD-box family protein is a kind of ATP dependent RNA helicase,which plays a critical role in RNA metabolism.The DEAD-box family proteins can affect cell proliferation,differentiation,and apoptosis through regulating the expression of oncogenes,tumor suppressor genes and tumor related signaling pathways.It plays the role in promoting or suppressing cancer.
