Perioperative safety of Tibetan children with congenital heart disease undergoing cardiac surgery and anesthesia in low-altitude area
10.11817/j.issn.1672-7347.2017.11.008
- VernacularTitle:西藏先天性心脏病患儿在低海拔地区行手术麻醉的围手术期安全性
- Author:
Yundan PAN
1
;
Jiaojiao NIU
;
Gang QIN
;
Lu WANG
;
Fan ZHANG
;
E WANG
Author Information
1. 中南大学湘雅医院麻醉科
- Keywords:
high-altitude medicine;
congenital heart disease;
anesthesia;
perioperative period
- From:
Journal of Central South University(Medical Sciences)
2017;42(11):1288-1292
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the clinical parameters and short-term prognosis of Tibetan high-altitude area children with congenital heart disease undergoing surgery and anaesthesia in low-altitude area,and to investigate the perioperative safety of the treatment.Methods:From January,2016 to December,2016,14 children with congenital heart disease who underwent surgery were assigned into 2 groups (n=7 each):the high-altitude area group (X group,children from Tibetan Autonomous Region) and the low-altitude area group (H group,children from Hunan Province).Echocardiography data,perioperative hemodynamic changes,postoperative recovery,complication and perioperative serum N terminal pro B type natriuretic peptide (NT-proBNP) levels were recorded.Results:There were no significant differences in cardiac structure and function between the 2 groups,while the incidence of pulmonary hypertension in the X group was significantly higher than that in the H group (P＜0.05).There were no significant differences in perioperative hemodynamics between the 2 groups (P＞0.05),while the duration in ICU in the X group was longer than that in the H group and the serum NT-proBNP level in the X group was higher than that in the H group (P＜0.05).Conclusion:For children with congenital heart disease in Tibetan high-altitude area,undergoing surgery in low-altitude area contributes to a steady perioperative hemodynamics and helps to increase the perioperative safety.There may be a higher risk of postoperative cardiac dysfunction in Tibetan children than that in low-altitude area.
