Analysis of adverse drug reactions induced by compound Kushen injection in Qingdao central hospital

VernacularTitle:青岛市中心医院复方苦参注射液药品不良反应报告分析
Author: Xuedong YU ¹ ; Na ZHU ; Chuanxin GENG
Author Information

1. 266500,山东省青岛慧康医院药剂科
Keywords: Traditional Chinese drug adverse reaction; Compound Kushen injection; Adverse drug reaction reporting systems; Drug monitoring; Rational use of drugs
From: International Journal of Traditional Chinese Medicine 2018;40(9):832-835
CountryChina
Language:Chinese
Abstract: Objective The adverse drug reaction (ADR) reports of compound Kushen injection in Qingdao Central Hospital were analyzed to improve the level of safe and rational use of drugs.Methods We investigated 35 cases of severe ADR reports induced by compound Kushen injection in Qingdao Central Hospital from 2016.09 to 2018.03 retrospectively.Then the type of report,relevance evaluation and prognosis,ADR occurrence and recovered time,involved system/organs and main clinical manifestations were analyzed.Results The new moderate and new severe ADR incident were 51.4％ of 35 ADR reports.Twenty-nine cases of the ADR were occurred 30 minutes after injection.Twenty-three cases of ADR clinical symptoms can be recovered after 30 minutes.The main ADR was the digestive system reaction,followed by the neural system,respiratory system and cardiovascular system.Conclusions It is important to pay attention to the occurrence of compound Kushen injection ADR and strengthen its monitoring.