Effect on Guizhi-Fuling decoction and Danggui-Shaoyao decoction combined with metformin for follicle numbers and ovarian volume of fueling the polycystic ovarian syndrome
10.3760/cma.j.issn.1673-4246.2018.05.004
- VernacularTitle:桂枝茯苓丸合当归芍药汤联合二甲双胍片对肥胖型多囊卵巢综合征卵巢体积及卵泡数目的影响
- Author:
Zhiqin YANG
1
;
Bing YAN
Author Information
1. 053000,河北省衡水市哈励逊国际和平医院生殖医学科
- Keywords:
Polycystic ovary syndrome;
Gui Zhi Fu Ling Wan;
Dang Gui Shao Yao Tang;
Metformin;
Clinical study
- From:
International Journal of Traditional Chinese Medicine
2018;40(5):398-401
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of Guizhi-Fuling decoction and Danggui-Shaoyao decoction combined with metformin in patients with polycystic ovarian syndrome. Methods A total of 120 patients with fueling the polycystic ovarian syndrome were enrolled and divided into two group by random number table method, the treatment group (60 patients) and the control group (60 patients). Patients in the control group were treated with metformin, and those in the treatment group with Guizhi-Fuling decoction and Danggui-Shaoyao decoction plus metformin for 6 menstrual cycle. The vagina or rectum two-dimensional ultrasound was detected by follicle numbers (FN) and ovarian volume (OV). The height, weight, BMI calculation were recorded and evaluated before and after treatment. Results After treatment and follow-up, the OV (2.4 ± 1.5 cm3 vs. 4.7 ± 2.6 cm3, t=5.935; 1.6 ± 0.8 cm3 vs. 2.9 ± 1.3 cm3, t=-6.597), FN (8 ± 2 vs. 10 ± 2, t=-5.477; 6 ± 1 vs. 8 ± 2, t=-6.928) and BMI (20.5 ± 2.6 kg/m2 vs. 23.8 ± 2.7 kg/m2, t=-6.866; 20.1 ± 1.3 kg/m2 vs. 22.6 ± 1.7 kg/m2, t=-9.074) of the treatment group were significantly lower than those of the control group(P<0.01). Conclusions The Guizhi-Fuling decoction and Danggui-Shaoyao decoction combined with metformin can reduce the weight, ovarian volume, follicle numbers of PCOS patients.
