A Case of Pentastomiasis at the Left Maxilla Bone in a Patient with Thyroid Cancer.
10.3347/kjp.2017.55.4.433
- Author:
Eunae Sandra CHO
1
;
Seung Wook JUNG
;
Hwi Dong JUNG
;
In Yong LEE
;
Tai Soon YONG
;
Su Jin JEONG
;
Hyun Sil KIM
Author Information
1. Department of Oral Pathology, Oral Cancer Research Institute, Yonsei University College of Dentistry, Seoul 03722, Korea. khs@yuhs.ac
- Publication Type:Case Report
- Keywords:
Pentastomida;
parasite;
osteonecrosis;
bisphosphonate-associated osteonecrosis of the jaw (BRONJ)
- MeSH:
Biopsy;
Bone and Bones;
Diagnosis, Differential;
Humans;
Jaw;
Male;
Mandible;
Maxilla*;
Maxillary Sinus;
Middle Aged;
Nasal Cavity;
Neoplasm Metastasis;
Osteolysis;
Osteonecrosis;
Palate;
Parasites;
Pentastomida;
Respiratory System;
Suppuration;
Thyroid Gland*;
Thyroid Neoplasms*;
Viscera;
Wounds and Injuries
- From:The Korean Journal of Parasitology
2017;55(4):433-437
- CountryRepublic of Korea
- Language:English
-
Abstract:
Pentastomiasis, a zoonotic parasite infection, is typically found in the respiratory tract and viscera of the host, including humans. Here, we report for the first time an extremely rare case of intraosseous pentastomiasis in the human maxilla suffering from medication related osteonecrosis of the jaw (MRONJ). A 55-year-old male had continuously visited the hospital for MRONJ which had primarily developed after bisphosphonate and anti-neoplastic administration for previous bone metastasis of medullary thyroid cancer. Pain, bone exposure, and pus discharge in the right mandible and left maxilla were seen. Osteolysis with maxillary cortical bone perforation at the left buccal vestibule, palate, nasal cavity, and maxillary sinus was observed by radiologic images. A biopsy was done at the left maxilla and through pathological evaluation, a parasite with features of pentastome was revealed within the necrotic bone tissue. Further history taking and laboratory evaluation was done. The parasite was suspected to be infected through maxillary open wounds caused by MRONJ. Awareness of intraosseous pentastomiasis should be emphasized not to be missed behind the MRONJ. Proper evaluation and interpretation for past medical history may lead to correct differential diagnosis and therapeutic intervention for parasite infections.
