Study on the quality standard of improvement of Tongluo-Zhujing pills
10.3760/cma.j.issn.1673-4246.2018.04.014
- VernacularTitle:通络驻景丸质量标准研究
- Author:
Yuying HU
1
;
Kangle LI
;
Mingjie LI
;
Rongguo SHANG
;
Hua AI
;
Xiaoqin LEI
Author Information
1. 三二〇一医院药学部
- Keywords:
Chromatography;
thin layer;
Chromatography;
high pressure liquid;
Quality control;
Tongluo-Zhujing pills
- From:
International Journal of Traditional Chinese Medicine
2018;40(4):350-353
- CountryChina
- Language:Chinese
-
Abstract:
Objective To improve the quality standard of Tongluo-Zhujing pills.Methods We added the identification ofradix notoginseng andtypha orientalisby TLC and determination of the content of wedelolactone by HPLC. The study used Agilent ZORBAX SB-C18 (4.6 mm × 250 mm, 5 μm) column and the velocity of flow manufactured by the proper proportion was 1 ml/min. The detection wavelength was 249 nm . Results The new method could well identify radix notoginsengandtypha orientalis. The calibration curves of wedelolactone was in good linearity over the range of 0.064-0.642 μg (r=0.999 7) and the average recovery was 98.74%(RSD=1.61%).Conclusions The quality standard of Tongluo-Zhujing pills was proved effectively.
