Progress of circulating tumor cells in clinical application

VernacularTitle:循环肿瘤细胞在临床应用中的研究进展
Author: Luojun CHEN ¹ ; Na LI ; Jingyuan TIAN ; Qibin SONG ; Jinming YU
Author Information

1. 430060,武汉大学人民医院肿瘤中心
Keywords: Neoplasm circulating cells; Diagnosis; Prognosis; Liquid biopsy
From: Journal of International Oncology 2018;45(9):552-555
CountryChina
Language:Chinese
Abstract: Circulating tumor cells (CTCs)are cancerous cells that shed from the primary tumor or metastases into the bloodstream. The currently clinical applicability of CTCs approved by the US Food and Drug Administration (FDA)is that CTCs can be prognostic biomarker for patients with metastatic breast cancer, prostate cancer and colorectal cancer. CTCs also have great potential in the prognosis assessment of other meta-static or localized tumors,as well as early screening of tumors,analysis of molecular profiling,guiding treat-ment decisions,and monitoring of treatment response. Currently,various studies are being carried out to further explore the clinical application of CTCs,and provide new strategies and new prospects for individualized and precise treatment of cancer patients.