Immunological regulation of CD70/CD27 pathway and the expression of CD70 in tumor
10.3760/cma.j.issn.1673-422X.2018.08.008
- VernacularTitle:CD70/CD27通路参与的免疫调节及CD70在肿瘤中的表达
- Author:
Zhenzhen LIU
1
;
Yingjun KONG
;
Wenxue SUN
;
Shimin LI
;
Min ZHANG
;
Hesong YIN
Author Information
1. 150001,哈尔滨医科大学附属第一医院呼吸内科
- Keywords:
Immunity,cellular;
Neoplasms;
CD70/CD27 pathway
- From:
Journal of International Oncology
2018;45(8):487-489
- CountryChina
- Language:Chinese
-
Abstract:
CD70/CD27 pathway plays an important role in human immune regulation.The role of CD70/CD27 pathway in immune regulation is mainly to promote the activation and proliferation of T cells,induce the differentiation and formation of effector T cells and memory T cells,and interfere with regulatory T cells.In addition,the high level of CD70 expression in some tumor cells provides a new way for tumor immunotherapy.
