Expression and significance of tripartite motif family proteins in hepatocellular carcinoma

VernacularTitle:三结构域蛋白家族在肝细胞癌中的表达及意义
Author: Meng LI ^{1
,

2} ; De HE
Author Information

1. 524023湛江,广东医科大学研究生院
2. 南方医科大学附属深圳宝安医院普通外科
Keywords: Carcinoma,hepatocellular; Tripartite motif family
From: Journal of International Oncology 2018;45(6):375-378
CountryChina
Language:Chinese
Abstract: Tripartite motif (TRIM) family,a very important protein family,has various functions in cellular biological processes including intracellular signal transduction,cell growth and apoptosis,innate immunity,autophagy and tumorigenesis.The specific expressions of TRIM in hepatocellular carcinoma are proved by many researches,which are closely related to the occurrence,metastasis and prognosis of hepatocellular carcinoma.TRIM are expected to be markers for the occurrence and development of hepatocellular carcinoma,and have broad prospects in the early diagnosis,therapy and prognosis of hepatocellular carcinoma.