Mechanism of ductal carcinoma in situ to invasive breast cancer
10.3760/cma.j.issn.1673-422X.2018.06.012
- VernacularTitle:乳腺导管内原位癌浸润机制
- Author:
Zhiyu LI
1
;
Qi WU
;
Shengrong SUN
Author Information
1. 430060,武汉大学人民医院乳腺甲状腺外科
- Keywords:
Breast neoplasms;
Carcinoma,intraductal,noninfiltrating;
Disease progression
- From:
Journal of International Oncology
2018;45(6):368-370
- CountryChina
- Language:Chinese
-
Abstract:
Ductal carcinoma in situ (DCIS) is a precursor of invasive ductal breast cancer,and up to 40％ of these lesions will progress to invasive disease if untreated.The micro-environment,genetic aberrations,signal pathways and epigenetics play important roles during the infiltration and transformation of DCIS.Further studies of the infiltration and transformation of DCIS will promote the accurate assessment and prognosis prediction of the patients with DCIS,for finding a comprehensive evaluation standard and the balance between the over and low treatment.
