Mechanism of microRNA-495 in glioma
10.3760/cma.j.issn.1673-422X.2018.06.010
- VernacularTitle:微小RNA-495在神经胶质瘤中的作用机制
- Author:
Yuanyuan ZHANG
1
;
Shuxia ZHU
Author Information
1. 256600,滨州医学院附属医院儿童血液与神经病区
- Keywords:
MicroRNAs;
Glioma;
Signal transduction
- From:
Journal of International Oncology
2018;45(6):362-364
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNA-495 (miR-495) is abnormally expressed in many tumors,especially in glioma.It involves in the proliferation,apoptosis,cycle regulation,metabolism,invasion and metastasis of tumor cells by regulating cyclin-dependent kinase 6 signaling pathway,glucose transporter type 1 signaling pathway,MYB signaling pathway,growth factor-independent 1 signaling pathway and high-mobility group nucleosome-binding domain 5 signaling pathway.Further study of miRNA-495 might provide a novel direction for clarifying the pathogenesis,diagnosis and treatment of glioma.
