Role of microRNA-373 in tumor
10.3760/cma.j.issn.1673-422X.2018.06.008
- VernacularTitle:微小RNA-373在肿瘤中的作用
- Author:
Kai SHEN
1
;
Fang SHAO
;
Tongbao FENG
;
Chunjian QI
Author Information
1. 213000,南京医科大学附属常州市第二人民医院肿瘤研究所
- Keywords:
Neoplasms;
MicroRNAs;
Neoplasms metastasis;
Gene expression regulation
- From:
Journal of International Oncology
2018;45(6):355-357
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs are non-coding small RNAs that participate in the regulation of post transcriptional gene expression.MicroRNAs play the roles of inhibiting cancer or promoting cancer in different tumors.MicroRNA-373 is one of the members of the microRNA-520/373 family,which is involved in cancer anoxic response and DNA damage repair.MicroRNA-373 is abnormal expressed in breast cancer,glioma,lung cancer,prostate cancer and other tumors,which may play an important role in tumor development process,especially in tumor invasion and migration.