Pathogenesis of ethanol-induced esophageal cancer
10.3760/cma.j.issn.1673-422X.2018.02.014
- VernacularTitle:乙醇致食管癌发病机制
- Author:
Tao LIN
1
;
Dongchun MA
;
Hua WANG
;
Mingran XIE
;
Tianci ZHANG
Author Information
1. 安徽医科大学附属省立医院胸外科
- Keywords:
Esophageal neoplasms;
Ethanol
- From:
Journal of International Oncology
2018;45(2):119-121
- CountryChina
- Language:Chinese
-
Abstract:
Ethanol is one of the major risk factors for esophageal cancer.The main mechanisms of ethanol induced esophageal cancer include the direct carcinogenesis of acetaldehyde,the genetic polymorphism of enzymes related to alcohol metabolism,the carcinogenic effect of reactive oxygen species,the disorder of nutrient metabolism induced by ethanol,and the synergistic effect of ethanol and tobacco.
