Roles of platelets in tumor progression
10.3760/cma.j.issn.1673-422X.2018.02.010
- VernacularTitle:血小板在促进肿瘤进展中的作用
- Author:
Luojun CHEN
1
;
Jingyuan TIAN
;
Na LI
;
Qibin SONG
Author Information
1. 430060,武汉大学人民医院肿瘤中心
- Keywords:
Blood platelets;
Neoplasms
- From:
Journal of International Oncology
2018;45(2):103-106
- CountryChina
- Language:Chinese
-
Abstract:
Platelets play important roles in tumor progression.Increased platelets count is associated with poor overall survival and prognosis.Tumor cell-induced platelet activation and platelet-induced tumor growth form a malignant amplification loop which plays a crucial role in tumor cell proliferation,metastasis and angiogenesis.Antiplatelet therapy may break the platelet-tumor amplification loop and play a key role in reducing tumor metastasis.
