Connexin 43 and tumors
10.3760/cma.j.issn.1673-422X.2018.01.007
- VernacularTitle:间隙连接蛋白43与肿瘤
- Author:
Xiaorong WEN
1
;
Hongmei MO
;
Tao GUO
;
Mengting DING
Author Information
1. 518000,深圳市龙岗区第三人民医院妇科
- Keywords:
Connexin 43;
Neoplasms;
Cell communication
- From:
Journal of International Oncology
2018;45(1):32-34
- CountryChina
- Language:Chinese
-
Abstract:
Cell gap junction is a special protein channel.Gap junction-mediated exchange of information between cells is crucial for cell growth,differentiation and tissue homeostasis.Connexin 43 (Cx43) is one of the members of the gap junction protein family.In recent years,researches show that abnormal Cx43 gene expression leads to the cell gap junctional communication dysfunction,which is closely related to the occurrence,metastasis and prognosis of a variety of tumors.Cx43 is expected to become a new target for clinical diagnosis and treatment of tumors.
