A Case of Secondary Amyloid Colitis in Rheumatoid Arthritis.
- Author:
Jae Wan CHO
1
;
Hiun Suk CHAE
;
Kuk Hee IM
;
Tae Ho KIM
;
Gang Mun LEE
;
Sung Soo KIM
;
Chang Don LEE
;
Gyu Yong CHOI
;
In Sik CHUNG
;
Hee Sick SUN
;
Yi So MAENG
;
Chang Hyuk AN
Author Information
1. Department of Internal Medcine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Case Report
- MeSH:
Abdominal Pain;
Aged;
Amyloid*;
Amyloidosis;
Arthritis, Rheumatoid*;
Biopsy;
Colitis*;
Colon;
Colon, Sigmoid;
Diabetes Mellitus;
Diarrhea;
Extracellular Space;
Female;
Hemorrhage;
Humans;
Hypertension;
Ileum;
Microscopy;
Plaque, Amyloid;
Ulcer
- From:Journal of the Korean Society of Coloproctology
2000;16(2):125-130
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Amyloidosis is known as a disease caused by the deposition of a insoluble and fibrous amyloid protein in the extracellular space of various organs and tissue. Intestinal amyloid deposition may develop motility disturbance, malabsorption, bleeding and perforation. A 70-year old woman with lower abdominal pain, watery diarrhea was admitted and had the past history of diabetes mellitus, hypertension for 8 years and rheumatoid arthritis for 10 year. On colonoscopic examination for evaluation of diarrhea, multiple edematous and shallow ulcers was found from distal sigmoid to terminal ileum. A green colored positive birifringent stained amorphous material was found in polarizing microscopy of colon biopsy specimen stained with Congo-red on microscopic examination,. We report a case of amyloidosis causing colon ulcers confirmed by colonoscopic biopsy with review literature.