Sensitivity prediction of preoperative chemoradiotherapy in patients with rectal cancer and the clinical application

VernacularTitle:直肠癌术前放化疗的敏感性预测及临床应用
Author: Xueqi YAN ¹ ; Jundong ZHOU ; Jinchang WU
Author Information

1. 215000,南京医科大学附属苏州医院放疗科
Keywords: Rectal neoplasms; Preoperative concurrent chemoradiotherapy; Molecular markers
From: Journal of International Oncology 2017;44(12):944-947
CountryChina
Language:Chinese
Abstract: Some of the patients with rectal cancer are less sensitive to preoperative concurrent chemoradiotherapy (CCRT).Patients who are resistant to CCRT have a poor local tumor control and CCRT may also increase adverse reactions.The sensitivity of rectal cancer patients to CCRT can be predicted by magnetic resonance imaging (MRI),positron emission tomography,serum carcinoembryonic antigen,molecular biomarkers and gene expression profiling before treatment.According to the predicted results,the clinicians are instructed to choose individualized treatment for the patients so that the therapeutic effects of rectal cancer are further improved.