Interferon alpha-inducible protein 27 and tumor

VernacularTitle:α干扰素诱导蛋白27与肿瘤
Author: Honglu LIU ¹ ; Xin LIU ; Yan CHEN ; Ping LI ; Xicai WANG
Author Information

1. 650118,云南省肿瘤医院昆明医科大学第三附属医院肿瘤研究所
Keywords: Apoptosis; Neoplasms; Interferon alpha-inducible protein 27
From: Journal of International Oncology 2017;44(12):914-917
CountryChina
Language:Chinese
Abstract: Interferon alpha-inducible protein 27 (IFI27) is a newly discovered protein that participates in biological functions such as apoptosis,cell autophagy,oncolytic and immunoregulation.It also plays a major role in promoting tumor development,such as in breast cancer,ovarian cancer,liver cancer,squamous cell carcinoma and so on.Besides,studies have shown that IFI27 can interact with signal transducer and activator of transcription 1,microRNAs,interferon regulatory factor 4 and other genes,which promotes the development of tumors.Therefore,IFI27 is expected to be a marker for the occurrence and development of tumors,providing a new target for cancer therapy.