Histone modification in breast cancer
10.3760/cma.j.issn.1673-422X.2017.10.013
- VernacularTitle:组蛋白修饰在乳腺癌中的研究进展
- Author:
Jiahui FANG
1
;
Changshan WANG
;
Yongfeng JIA
Author Information
1. 内蒙古医科大学病理教研室
- Keywords:
Epigenesis,genetic;
Histones;
Breast neoplasms
- From:
Journal of International Oncology
2017;44(10):775-778
- CountryChina
- Language:Chinese
-
Abstract:
Epigenetic regulation plays an important role in breast cancer research.The epigenetic modification of histone mainly affects the occurrence and development of breast cancer by adding and removing methyl,acetyl and phosphate groups under the action of various enzymes.Because of its reversible regulatory process,it can provide advantage for the affected region to return to the normal genome state.Clinically,this can be used to develop a variety of drugs for patient diagnosis and treatment and to provide treatment targets.
