Research process of APOBEC3B in breast cancer
10.3760/cma.j.issn.1673-422X.2017.09.014
- VernacularTitle:APOBEC3B在乳腺癌中的研究进展
- Author:
Rongrong DONG
1
;
Xuexin HE
;
Jiali JI
Author Information
1. 浙江大学医学院附属第二医院肿瘤内科
- Keywords:
Breast neoplasms;
Mutation;
Prognosis;
Apolioprotein B mRNA-editing enzyme catalytic polypeptide 3B
- From:
Journal of International Oncology
2017;44(9):696-699
- CountryChina
- Language:Chinese
-
Abstract:
APOBEC3B is one member of APOBEC with the activity of cytosine deaminase.Researches show that APOBEC3B can take park in the development and progression of breast cancer by means of mediating the genome mutations,which can promote cancer metastasis and drug resistance,thus influencing the treatment effect of patients with cancers.APOBEC3B is closely related with clinical prognosis of breast cancer,which has a potential value in the early diagnosis and biological therapy of breast cancer and provides a new hope for the treatment of breast cancer.
