Molecular targeted therapy in glioblastoma
10.3760/cma.j.issn.1673-422X.2017.09.012
- VernacularTitle:恶性胶质瘤的分子靶向治疗
- Author:
Yang NAN
1
;
Yue ZHONG
Author Information
1. 300052,天津医科大学总医院神经外科
- Keywords:
Glioma;
Targeted therapy
- From:
Journal of International Oncology
2017;44(9):689-692
- CountryChina
- Language:Chinese
-
Abstract:
Glioblastomas is the most common malignant primary brain tumors and the prognosis is very poor.With the development of tumor molecular biology,molecular targeted therapy for glioblastomas has become an integral part of its comprehensive treatment.Targeted therapy drugs of glioblastomas are emerging,including tyrosine kinase inhibitors,histone deacetylase inhibitors,phosphatidylinositol 3-kinase inhibitors,hypoxia inducible factor-1 α inhibitors,sodium-potassium pump inhibitors,et al.With the development of new molecular targeted therapy,more effective or even treatment measures of glioblastomas might be found,which can provide a new approach for the individualized treatment of glioblastomas.
