Application of aptamer in the study of cancer stem cells

VernacularTitle:适配子在肿瘤干细胞研究中的应用
Author: Yonghua PENG ¹ ; Li PENG ; Zhiman LIANG ; Xingmei ZHANG
Author Information

1. 南方医科大学基础医学院神经生物学教研室
Keywords: Neoplastic stem cells; SELEX aptamer technique; Neoplasms
From: Journal of International Oncology 2017;44(9):672-675
CountryChina
Language:Chinese
Abstract: Cancer stem cells have self-renewal and multilineage differentiation potentials,which play important roles in tumorigenesis,metastasis,recurrence and resistance to chemical therapy and radiotherapy,and so on.It is the hotspot of tumor research recently.Aptamer is a small molecular oligonucleotide with high targeting ability and affinity,which is a new type of nucleic acid in the diagnosis and treatment of cancer.Now more and more research is being done on the aptamer is applied in the diagnosis and treatment of cancer stem cells,which provides a new research tool for the diagnosis and treatment of cancer stem cells.