Research progress of DNA hydrogel
10.13220/j.cnki.jipr.2017.10.006
- VernacularTitle:DNA凝胶的研究进展
- Author:
Jiao-Jiao CHEN
1
;
Shi-Rui YUAN
;
Ya SONG
;
Qiao-Fang MA
;
Xiao-Le QI
;
Zheng-Hong WU
Author Information
1. 211198南京,中国药科大学药学院,药剂系
- Keywords:
DNA hydrogels;
stimuli-response;
drug controlled-releasing;
targeted therapy;
biosensor
- From:
Journal of International Pharmaceutical Research
2017;44(10):935-940,946
- CountryChina
- Language:Chinese
-
Abstract:
DNA hydrogels,combining the features of both DNA and hydrogels macromolecules,are endowed with the biologi?cal characters of DNA and the framed structure of hydrogels skeleton.Currently,most DNA hydrogels can achieve sensitive response to temperature,pH,light,and small molecule stimuli,by introducing specific groups or sequences into their backbone.Therefore, the functional properties of DNA hydrogels can be further improved.In this review,we introduce the mentioned stimuli-response DNA hydrogels,as well as their applications in drug controlled-releasing,targeted cancer therapy,biosensor and others.Finally,the pros?pects in the development of DNA hydrogels are also mentioned.
